Cord Blood Transplantation Provided Long-term Remission in a Case of Adult T-cell Leukemia-lymphoma (ATL) with Myelofibrosis.

نویسندگان

  • Hidehiro Itonaga
  • Jun Taguchi
  • Takeharu Kato
  • Shinya Sato
  • Yasushi Sawayama
  • Yoshitaka Imaizumi
  • Daisuke Niino
  • Tomoko Hata
  • Takuya Fukushima
  • Koichi Ohshima
  • Yasushi Miyazaki
چکیده

A 53-year-old man was diagnosed with adult T-cell leukemia-lymphoma (ATL) acute type transformed from chronic type. A bone marrow analysis showed diffuse infiltration of abnormal lymphocytes and diffuse fibrotic change. He received unrelated cord blood transplantation (CBT) following reduced-intensity conditioning with complete remission of ATL after two courses of chemotherapy and achieved neutrophil and platelet engraftment. At 99 days after CBT, a bone marrow biopsy showed apparent resolution of myelofibrosis. These results suggest the therapeutic potential of CBT for patients with chemosensitive ATL with myelofibrosis.

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عنوان ژورنال:
  • Internal medicine

دوره 55 2  شماره 

صفحات  -

تاریخ انتشار 2016